This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakehouses, or ensuring data lineage and reproducibility in biological research. Covers data management, annotation, ontologies (genes, cell types, diseases, tissues), schema validation, integrations with workflow managers (Nextflow, Snakemake) and MLOps platforms (W&B, MLflow), and deployment strategies.

此技能适用于使用LaminDB——一种开源的生物学数据框架，可使数据具备可查询性、可追溯性、可重复性和FAIR原则。适用于管理生物学数据集（如单细胞RNA测序、空间转录组、流式细胞术等）、跟踪计算工作流、使用生物学本体论对数据进行整理与验证、构建数据湖仓，以及确保生物学研究中的数据溯源与可重复性。涵盖数据管理、注释、本体论（基因、细胞类型、疾病、组织）、模式验证、与工作流管理工具（Nextflow、Snakemake）及MLOps平台（Weights & Biases、MLflow）的集成，以及部署策略。